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In old female Sprague-Dawley rats, curcumin treatment decreased the rate of A deposition and despite receiving an intracerebroventricular infusion of A , both pre- and post-synaptic protein levels increased by orally administrating 500 ppm curcumin for 2 months prior to A infusion

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and for SchirmerM_2024, data were obtained from the supplementary Data of the corresponding publication

The procedures of animal study were approved by the Institutional Animal Care and Use Committee (IACUC2017O04) of National Laboratory Animal Center, National Applied Research Laboratories, Taiwan

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